Where to Stay: San Francisco A guide to the city's best digs

The City by the Bay boasts about as many neighborhoods as hotels. Luckily for you, we've taken it upon ourselves to round up the cream of the crop, whether you want to vacation like a rockstar, or just think you're Turning Japanese. Here are our picks:

Hotel Adagio
550 Geary Street; Downtown; 415.775.5000
Proudly mounted in the Theatre District amidst the burgeoning heart of downtown, Adagio hides its contempo-upscale aesthetic (spread out across 171 rooms and a hip lounge dubbed Mortimer Bar) inside a Spanish colonial revival building originally erected in 1929.
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Grand Hyatt San Francisco
345 Stockton Street; Union Square; 415.398.1234
The jack of all trades of SF lodging, the Grand Hyatt's a 660-room mega-hotel catering to both the business & recreational set with its cocktail lounge, American bistro, and shloads of amenities.
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Mystic Hotel
417 Stockton Street; Union Square; 415.400.0500
You'd think a hotel owned by renowned chef Charlie Palmer would serve superlative cuisine... and you'd be right! Witness Mystic Hotel, a modernized, Union Square-adjacent home away from home offering dapper accommodations, top-notch vittles, and one of the San Fran's hottest speakeasies.
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The Fairmont
950 Mason Street; Nob Hill; 415.772.5000
Located at the most important locus in SF (where all of the cable car lines meet!), Fairmont offers almost-too-easy access to Downtown, FiDi, Union Square, and Fisherman's Wharf, not to mention unobstructed panoramic views of the city, and a restaurant with a freaking pool in the middle of it.
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Serrano Hotel
405 Taylor Street; Downtown; 415.885.2500
Just like the famed pepper found in the mountainous regions of the Mexican states of Puebla and Hidalgo, Serrano's a spicy-hot, four-star boutique hotel located just blocks away from Union Square that features in-room spa services and a Yoga channel on every TV, making the painstaking task of finding your chi easier than ever.
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Sir Francis Drake Hotel
450 Powell Street; Union Square; 415.392.7755
Not the 16th-century sea captain & navigator, but certainly worthy of housing him, Sir Francis Drake is a Union Square hotel decidedly dripping with class and sophistication. With food plated by Top Cheftestants Jennifer Biesty & Tim Nugent and the speakeasy known as Bar Drake, you'll have plenty of exploring to do yourself.
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Phoenix Hotel
601 Eddy Street; Tenderloin; 415.413.0900
Planted on the edge of the Tenderloin, Phoenix Hotel prides itself on its atmosphere, knowledgeable staff, and rockin' guest list that has included such talent as The Shins, Little Richard, and Pearl Jam.
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Hotel Kabuki
1625 Post Street; Japantown; 415.922.3200
Established in the heart of Japantown, Kabuki brings together Eastern and Western influences to create a relaxing environment that North and South just wouldn't understand.
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