Surly Brewing Co. (address and info)
Weren't Midwesterners supposed to be all nice and friendly? Surly made a name for itself with the aggressive, addictive bitterness of Furious, and hasn't looked back, turning out big, bold, must-have beers like their Abrasive Ale (a double IPA) and Darkness, their excellent rendition of the must-have, released once a year, horde-worthy stout. Minnesota's not lacking for exciting breweries, but nothing has come close to challenging Surly's supremacy.
Southern Prohibition Brewing (address and info)
Like so many other breweries in the South, the Hattiesburg operation is young, but they’ve quickly expanded into and experimented with more styles of beer than many of their counterparts, canning regular rotations like the Suzy B. Blonder, Fire Ant Red Ale, and Jack the Sipper ESB. But for their envelope-pushers, look to the season cicada series, like the shockingly well-balanced, award-winning Sinister Minister, a malty, hoppy black IPA.