"Sulfites can cause allergy and asthma symptoms, but they don't cause headaches," Frederick Freitag, associate director of the Diamond Headache Clinic in Chicago and a board member of the National Headache Foundation, told the Wall Street Journal.
In Champagne's case specifically, some attribute the headache symptoms to the higher-than-normal sugar content of bubbly. Others will claim some grape strains can trigger headaches by themselves.
But the science here is murky at best. There is no way to know what specific grape strains may cause a certain body to react negatively. And while sugar does dehydrate you -- which can lead to a headache -- the sugar content present in Champagne is probably not what is making your noggin pound. Especially if you don't usually get headaches when you eat a chocolate bar, for instance.