Fortified for the moment, make your way six blocks up Main Street to 21c Museum Hotel, which is open 24-7-365, no admission fee required. You didn't think we'd let you get away without a little culture, did you? Regularly voted one of the top hotels in the country, this boutique is randomly and awesomely home to a world-class contemporary art museum. The exhibitions rotate regularly and are a fantastic way to spend any hour of the day, particularly the ghostly hour of 5am. And make sure not to miss the men’s room: the urinal is conveniently located along a one-way mirror with views out into the lobby, meaning you can watch the hotel take care of business while you, er, also take care of business?
Time to wash down that culture with a classic diner breakfast. Hail a cab over to Barbara Lee’s, a 24-hour joint in the Crescent Hill neighborhood. As with Mag Bar, every local has a Barbara Lee’s story and this place has seen its fair share of local characters over the years (think third shift blue-collar workers, sleepless University of Louisville students, and the requisite Kentucky good ol' boy) who roll in primarily during the twilight hours, when only diner food and no questions will do.