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1. Saison 178 Townsend St, San Francisco, CA 94107 (Soma)

Just across from AT&T Park is the Michelin-loved American eatery Saison. This ritzy restaurant offers views of the open kitchen right from your lush seat, so you can watch some of the best in the biz pull together all 18 courses of the nightly-changing menu. Distinctly noted as one of the most pricey restaurants in the entire state, most diners will assure you that Saison is worth every penny just to be in the mere presence of acclaimed Chef Joshua Skenes.

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2. Jamber Wine Pub 858 Folsom St, San Francisco, CA 94103 (Soma)

Jamber isn't a typical wine bar, it's a wine pub. All of the wines are from California, and they're all on tap. There are also over 10 beers on tap, also from California. To top it off, the SOMA spot has a really, really good food menu with things like mac & cheese pizza, poutine, and bacon-wrapped meatloaf. Oh, and one more thing: Jamber opens at 11:30am during the week and has outlets for your computer, so it's kind of the perfect place to wine and work.

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3. Twenty Five Lusk 25 Lusk St, San Francisco, CA 94107 (Soma)

Housed in a brick and timber SoMa warehouse erected in 1917, Twenty Five Lusk, few San Francisco bars deliver this combination of staggering size and striking beauty, . with 20ft-high ceilings, ample plush leather seating, and, the piece de resistance: stainless steel hanging fireplaces. But avert your eyes from the ambiance for a second, because you'll have to choose from a selection of 250-plus wines and elevated fare like fried burrata or braised rabbit and chevre ravioli.

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4. Umami Burger 242 King St, San Francisco, CA 94107 (Soma)

Named and acclaimed for the elusive ‘fifth taste,’ national chain Umami Burger aims to awaken your burger senses with its specially-coated patties and thoroughly perfected side pairings. Each bun is branded with a "U" and sandwiches carefully considered ingredients, like the restaurant’s signature burger topped with Parmesan frico, shiitake mushroom, roasted tomato, caramelized onions, and Umami ketchup.

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5. RN74 301 Mission St, San Francisco, CA 94105 (Soma)

Michael Mina's Mission Street French restaurant is a francophile's dream. The menu serves à la carte French dishes like steak tartare and lobster Thermidor, and also offers an eight-course tasting menu. The classiest thing about RN74 is its decor, which is styled like a Parisian train station. The permanent wine list is heavy on Burgundy pours, and the market wines are displayed on the wall like a train schedule.

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6. The Cavalier 360 Jesse St, San Francisco, CA 94103 (Soma)

An upscale pub-style joint in Soma from the folks behind Park Tavern, Marlowe, and S&R Lounge, The Cav serves a British-themed menu with hearty standouts like venison tartare; a bacon, caramelized onion, and cheddar burger; and Shepherd's pie.

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7. Marlowe 330 Townsend St, San Francisco, CA 94107 (Soma)

Named after the owners family butcher shop in Boston, it is no surprise that Marlowe, founded in San Francisco's swanky SoMA neighborhood, slings some of the Bay Area's best burgers. Not to be boxed in, this American-French bistro offers a diverse menu, which includes its signature Northern California oysters the perfect drink complement from its lengthy wine list.

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8. Park Tavern 1652 Stockton St, San Francisco, CA 94133 (North Beach)

If you're looking for a restaurant in North Beach packed with San Franciscans of all neighborhoods, head to Park Tavern. This upscale spot is homey and bustling, and the food is part Southern comfort, part English pub. Every table gets the famed lamb-and-beef Marlowe burger and a starter of smoky deviled eggs, but those in the know will get an extra order of eggs to put on their burger. Park Tavern is also a bonafide brunch hotspot with the best Bloody Marys and a menu filled with griddled goods (pancakes and more pancakes) and savory eggs. And that burger.

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9. Comstock Saloon 155 Columbus Ave, San Francisco, CA 94133 (North Beach)

From the folks behind Absinthe, Comstock is a classic San Francisco bar in North Beach. The throwback interior is outfitted with antique fans, a 150-year-old absinthe fountain, and the spot's original mahogany bar from 1907. The cocktails are just as classic as the bar, and the tie-and-vest wearing bartenders know how to mix pisco, lemon juice, and pineapple gomme into a standout punch.

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10. Original Joe's 601 Union Street, San Francisco, CA 94133 (North Beach)

Original Joe’s has been a North Beach staple for Italian delicacies since 1937 and is still the place to over-stuff yourself on classic Italian fare. Gleaming wood surfaces and classic furniture add to the restaurant’s atmosphere, making this a great spot for a date, but just warm enough to bring your parents to for a night out. Along with popularity come long lines and waits, so be sure to make a reservation.

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11. Trick Dog 3010 20th St, San Francisco, CA 94110 (The Mission)

Brought to you by The Bon Vivants, Trick Dog in The Mission's a marble- and steel-adorned cocktailery serving drinks from a Pantone-inspired menu with names from favorite song titles, along with bar bites like beer nuts, pickles, and cracklins.

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12. Namu Gaji 499 Dolores St, San Francisco, CA 94110 (The Mission)

This New Korean American restaurant is a family affair, owned by three brothers who utilize ingredients harvested from their own farm. Korean-inflected spins on favorites, like a pickled daikon-topped double cheeseburger and Korean tacos (nori replaces a tortilla shell, and is filled with marinated and grilled bulgogi beef, kimchi salsa, and spicy aïoli, are well-worth your time during the week, but the real star is the KFC (Korean Fried Chicken) brunch dish.

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13. The Abbot's Cellar 742 Valencia St, San Francisco, CA 94110 (The Mission)

The guys behind MK now have another spot, The Abbot's Cellar, that's right in the heart of The Mission. In a space that expertly balances hardwood floors, banquettes, chairs with stainless steel appliances, and marble tabletops, the chefs are offering up a menu that changes almost daily, inspired by close relationships with farmers and ranchers. Along with amazing food (pork loin, king salmon, and a variety of pasta), this place is super into beer, a fact reflected by a pretty deep menu of brews that come in both glass and bottle form.

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14. St. Vincent 1270 Valencia St, San Francisco, CA 94110 (The Mission)

This drinkery features both traditional wine bar food, like cheese plates, as well as traditional bar food. They also specialize in wine and have a list of more than 100 types that will cost you less than a Franklin a piece.

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15. Cerveceria de Mateveza 3801 18th St, San Francisco, CA 94114 (The Castro)

Cerveceria de MateVeza offers a rotating selection of guest beers on tap, plus nearly 100 more of the bottled variety. And should you feel the need for some comida con su cerveza, they also serve a number of delicious empanadas.

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16. Mission Bowling Club 3176 17th St, San Francisco, CA 94110 (The Mission)

Equipped with six lanes from an old Fort Bragg alley, MBC's ready to make your bowling experience feel all the more fancy with tufted leather booths where you can get down on fare that you'd be hard pressed to find in most bowling alleys, from gumbo-spiced red bean hushpuppies and harissa sauced lamb meatballs to Korean baby back ribs and English pea toast. And because bowling requires drinking, you'll also find a solid craft beer selection available in both pitchers and flights.

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17. Virgil's Sea Room 3152 Mission St, San Francisco, CA 94110 (The Mission)

A Mission cocktail bar that names its 'tails after local celebs like Dick Vivian and Frank Chu.

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18. Southpaw BBQ 2170 Mission St, San Francisco, CA 94110 (The Mission)

Southpaw BBQ is where dreams come true. Their Southern vibe, exposed brick walls, live-edge 20-seat Claro walnut bar, is exactly where you want to be eating brisket & ribs paired with American whiskeys and house-brewed beer. Their 80+ whiskey list is constantly growing, and if you join their whiskey club and try 40 of their offerings, any bottle of your choice is on the house.

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19. Hi Lo BBQ 3416 19th St, San Francisco, CA 94110 (The Mission)

Where there's wood, there's smoke, and when there's smoke, there's fire. Hi Lo is more than equipped to dole out as much meat as necessary by using a massive grill and smoker to cook up a variety of tasty BBQ, sold over the counter to their patrons, so if you're fixing for the itis, there's no need for a prescription.

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20. El Techo de Lolinda 2518 Mission St, San Francisco, CA 94110 (The Mission)

El Techo, the more casual version of the downstairs Argentinean steakhouse Lolinda, serves Latin American street food and pitchers of margaritas. You’re gonna want to get the chicharrones de carne, which come in half pound, one pound, or one and a half pound orders (in other words, you'll need to come with friends). These aren’t your basic sidewalk cracklin's -- these are massive fried chunks of roasted pork shoulder that you’ll devour with housemade tortillas, lime, salsa, and escabeche meant to be enjoyed alongside one of the best rooftop views San Francisco has to offer.

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21. Flour + Water 2401 Harrison St, San Francisco, CA 94110 (The Mission)

The pizza and pasta at Thomas McNaughton's Mission gem has consistently attracted a full house since opening in 2009. The Neapolitan-style pies are nothing short of excellent, and though the flavors change daily, you can expect a classic Margherita and meatier pizzas like salumi with Mangalitsa pancetta, stracciatella, broccoli rabe & Calabrian chili. And then there's the pasta. In a perfect world, you'd try each one on the menu and luckily, Flour + Water has a pasta tasting menu.

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22. Rich Table 199 Gough St, San Francisco, CA 94102 (Hayes Valley)

Rich Table's reclaimed-wood decor belies its menu of eclectic American dishes, which range from rainbow trout and rabbit leg to hangar steak and cured hamachi. There's also an impressive wine list, a range of beers on tap and in bottles, and handcrafted cocktails.

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23. AQ Restaurant & Bar 1085 Mission St, San Francisco, CA 94103 (Soma)

If you're looking for quintessential Californian cuisine, look no further than AQ. The upscale SOMA restaurant serves a tasting menu built around ingredients homegrown in northern California. The menu changes every night but sticks to the same theme, depending on the season. For lack of a better word, it's truly farm-to-table.

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24. Biergarten 424 Octavia St, San Francisco, CA 94102 (Hayes Valley)

With quintessential large mugs, sausages and sauerkraut, long picnic tables in the sun (hopefully), and a rotating selection of impressive German beers, Biergarten everything you want in, well, a beer garden. It’s owned by the masterminds behind Suppenküche, so you know you can bank on them having a way with Teutonic suds and snacks. With no roof, it’s not the ideal spot for a rainy day pint, but you’ll be clamoring for a space come summertime.

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25. TBD 1077 Mission St, San Francisco, CA 94103 (Soma)

TBD's a 50-seater resembling the interior if a pretty swank Tahoe cabin, but boasting 24-month-aged, cured iberico ham and delicious beer-and-wine cocktails.

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26. The Social Study 1795 Geary Blvd, San Francisco, CA 94115 (Fillmore)

As its name suggests, this hip, brick-walled coffee house in Fillmore is a chill place to hit the books. By day, this bustling cafe with ample seating doles out artisanal deli sandwiches, small bites, and dark roast espresso for the freelance crowd. By night, it becomes a cozy, den-like tavern with two-for-one tacos, soju cocktails, and a trip-hop soundtrack provided by local DJs.

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27. Maven 598 Haight St, San Francisco, CA 94117 (Lower Haight)

Maven is a chic bar and restaurant in Lower Haight that pairs all of its dishes with different cocktails. The highlight of the menu is the burger, which begins with beef that's ground with a few dashes of angostura bitters and is paired with the Mr. Wiggles cocktail, made with bourbon, amaro, vermouth, and bitters. The bar's morning cocktails make it a popular brunch spot, as do the duck hash and Bananas Foster French toast. The seating is all communal, and the best seats in the house are either on the second-floor loft or at the chef's counter.

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28. Rickybobby 400 Haight St, San Francisco, CA 94117 (Lower Haight)

You know it's a sweet place when it has two first names for its only name. And if you like cheap and hearty eats, soft lighting and crazy crap on the walls, you'll love Rickybobby.

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29. Per Diem 43 Sutter St, San Francisco, CA 94104 (Financial District)

Per Diem is a two-story restaurant in FiDi that specializes in the upscale combination of French and Northern Californian food. It has all your power lunch needs, with a menu of meat, salad, and sandwich entrées, all listed with suggested beverage pairings. It's closed on Sundays, so mark it for your next networking meal.

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30. Burritt Tavern 417 Stockton St, San Francisco, CA 94108 (Union Square)

Just off the Stockton Tunnel's front door, Burritt Tavern is Charlie Palmer's imbued-in-dude den inside the Mystic Hotel, a throwback adjacent to the namesake bar w/ a 122-seat dining room wrapped in century-old natural wood, and filled with gunmetal-finished, steel-framed booths that're privatized with a close-able velvet curtain, so no one'll hear you asking your friend what "imbued" means.

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31. Bluestem Brasserie 1 Yerba Buena Ln, San Francisco, CA 94103 (Soma)

Downtown's Bluestem Brasserie has a sleek vibe that's reminiscent of LA, which is exactly why it's so unique in the city by the bay. Floor-to-ceiling windows, big leather chairs, private booths, and a second-floor balcony create an upscale, power meal vibe that matches the menu of solid American food. Bluestem has the best brunch in the neighborhood, probably because it serves a special brunch-only burger that's topped with hash browns, breakfast sausage, bacon, house-made American cheese, and a fried egg. Hello, heaven.

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32. Jasper's Corner Tap & Kitchen 401 Taylor St, San Francisco, CA 94102

It's name along gives the impression that this Little Saigon spot might be a local dive plastered in graffiti and the sticky remnants of spilled beer, but Jasper's is the compete opposite. A clean-cut answer to less-than-desirable beer bars, this white leather palace rotates through 18 taps with craft beers from all along the West coast and offers upscale takes on standard bar food wth shareable plates of deviled eggs and greedy portions of sauce-slathered ribs and hearty meatloaf.

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33. Redford 673 Geary St, San Francisco, CA 94102 (The Tenderloin)

A huge, actually-classy-and-not-stabby spot in the Tenderloin that's got two separate bar areas, eats like pot pie and a build-your-own pastrami sandwich board for two, and drinks like their Whiskey Plank: four shots of the "Brown of the Month".

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34. Leopold's 2400 Polk St, San Francisco, CA 94109 (Russian Hill)

Leopold’s is an Austrian beer hall on Polk Street known for its boots of beer, dirndl-wearing waitresses, and year-round Oktoberfest vibe. The dinner menu features authentic Austrian eats like wiener schnitzel, beef goulash, and house-made charcuterie. There are eight beers on tap and more by the bottle, plus wine from Eastern European regions.

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35. The Corner Store 5 Masonic Ave, San Francisco, CA 94118 (The Richmond)

The Corner Store is set in a completely renovated space that was once a soda shop and then a speakeasy. Now, it's a 20-seat, outdoor-patio-featuring restaurant dominated by a mix of wood and white tile. The menu mixes things up with both small and large plates, which include lamb shoulder pasta, roasted duck breast, and brioche dinner rolls.

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36. Tacolicious 2250 Chestnut St., San Francisco, CA (The Marina)

Two blocks down from the original (and now-closed) Chestnut St location, this outpost of Tacolicious is bigger and brighter than its predecessor. The gourmet taco shop's menu features the original tortilla-wrapped goods you know and love, all of which are made with locally-sourced ingredients. Expect near-authentic tacos filled with house-made chorizo and potatoes, Baja-style Pacific cod, and Guajillo chili-braised brisket. There's also a solid selection of tequila-heavy cocktails and beers from Mexico and California.

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37. The Tipsy Pig 2231 Chestnut St, San Francisco, CA 94123 (The Marina)

Brunch and the Marina go together like bacon and eggs (and bottomless mimosas), and The Tipsy Pig has all these things, plus everything else you could ever want in a gastropub. Outdoor patio? Check. 40 local and worldly brews? Check. Cocktails? You get the idea. You’re going to want to get here early on a Sunday morning to stake out a spot outside and stay here all day chowing down on huevos rancheros, old-fashioned doughnuts, and the killer burger.

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38. Bitters, Bock, and Rye 1117 Polk St, San Francisco, CA 94109

A sweet new Lower Nob cocktailery sporting barbecue and hot-sauce-augmentable, already-hot barbecue sauce, so you might as well order another cocktail right away to cool off.

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39. Comal 2020 Shattuck Ave, Berkeley, CA 94704 (Berkeley)

Located in über-cool Berkeley, Comal is an Oaxacan restaurant that's the brainchild of the former Phish manager. The menu includes whole roasted chickens, grilled fish tacos, and pork enchiladas. Even better is their hard-to-believe-spacious outdoor space, where you can sip on your choice of draft and bottled beers, wine, and some perfectly refreshing summer cocktails.

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40. Brotzeit Lokal 1000 Embarcadero, Oakland, CA 94606 (Oakland)

Sausage and seaside views -- need we say more? Owned and operated by an Oakland-born husband and wife duo, Brotzeit Lokal is an authentic German biergarten that marries dockside dining with house-made, Bavarian-inspired fare. The eponymous sausage platter -- featuring two links, crunchy sauerkraut, spätzle, and a warm, buttery bretzel -- is the heavy-hitting favorite of both brunch and dinner services, but an extensive list of light bites makes the rest of the menu just as solid. The outdoor patio, sporting bright picnic tables and warm Christmas lights, makes for a convivial ambience (especially if you happen to have a dog; the spot is totally puppy-friendly).

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41. The Hog's Apothecary 375 40th Street, Oakland, CA 94609 (Oakland)

The Hog's Apothecary in Oakland's Jewel Box area takes a modern approach to the beer hall concept, giving it an upscale twist with an expertly curated, sometimes-obscure lineup of local craft beer and gourmet bar snacks. With 33 rotating taps, you have your work cut out for you, but ordering one of the nightly flights is a sure-fire route to discovering your new favorite brew. Though the beer roster certainly takes center stage, the food is in no way an understudy, which you'll realize as soon upon biting into the pork belly and sauerkraut corndog. The stripped-down, industrial-style interior with communal tables provides a chic finishing touch.

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42. Freehouse 2700 Bancroft way, Berkeley, CA 94704 (Berkeley)

Housed (see what we did there?) in a historic building constructed in 1926, Freehouse seeks to be a neighborhood bastion of American values, from freedom of expression to equal opportunity. Specifically, equal opportunity to order from the food and drink menus and the freedom to express yourself on the regulation-sized pool table.

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43. American Oak 2319 Santa Clara Ave, Alameda, CA 94501 (East Bay)

With more than 100 varieties on the menu, Whiskey is most definitely king at American Oak. You can become a member of the "Personal Liberty League" once you've tried at least 100 of the whiskeys on offer, at which point you'll receive a custom-etched glass with your name on it. If you're thinking that whiskey is all this place has to offer, however, you've clearly never looked at the food menu full of American fare such as burgers and pizza.

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44. Moxy Beer Garden 3136 Sacramento St, Berkeley, CA 94702 (Berkeley)

A Berkeley beer garden with an awesome patio/garden and mouth-watering pub food like a burger with blue cheese and applewood-smoked bacon, vegan Buffalo wings, and Parmesan truffle fries.

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45. Public House & Mijita 24 Willie Mays Plaza, San Francisco, CA 94105 (Embarcadero)

Located at AT&T Park, home of the two-World-Series-titles-in-three-years Giants, Public House is an awesome spot that has a secret entrace to the stadium and allows you to take beers to go for the game, because no one wants to pay $8 for watery hop water...er, Miller Lite.

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46. West of Pecos 550 Valencia St, San Francisco, CA 94110 (The Mission)

This Massive Mission staple is an excellent go-to if you're rolling with a big group, especially if said group has a taste for Tex Mex with a slight SF twist like Dungeness Crabamole (you can probably figure out what that is) or green chile mac & cheese with cornbread crumbles. Continuing with the group thing, the drink options are deep on margarita pitchers and tequila-powered punch bowls.