"What would happen if Calvin was on Earth with an unlimited food supply, able to grow exponentially and reproduce, and become even more terrifying?" Wernick asked in regards to what would happen in a potential follow-up. But Reese was quick to point out they haven't fully fleshed out the idea. "We don't have anything concrete, but there are definite thoughts and possibilities."
What about it being a prequel? As for the recent internet rumor that Life supposedly sets up a Venom franchise in the Spider-Man universe, Wernick took it in stride. "It was a perfect storm of people connecting the dots to the wrong conclusion," he said. "Unfortunately, we weren't smart enough to connect those dots ourselves." Reese thought the Venom gossip was good for Life for another reason. "We should've spread the rumor," he said, "to help the box-office numbers."