The film opens when Boyd Holbrook's army sniper Quinn McKenna encounters a crashed Predator vessel in Mexico. Making a potentially fatal mistake, he makes off with some of the alien's technology. It ultimately lands with his son, Rory (ROOM's Jacob Tremblay), a genius with Asperger syndrome who plays with the gear like a video game. Bad idea.
Meanwhile, Munn's Casey Brackett, a biologist studying animal hybridization, is summoned to a mysterious government lab where Sterling K. Brown's Traeger is holding the visitor hostage for now. The curious thing about this particular Predator: He's got some human DNA, raising questions about just what the hell the Predators are up to and whether or not this is evidence of the existence of some star-crossed human-predator relationship. (Please, Hollywood, make that insane movie.)
Anyway, as our lizard-y bud starts rampaging, Brackett is hooked up with McKenna and his new pals, a ragtag crew of veterans who call themselves the Loonies, because they've all been deemed crazy for one reason or another. When members of this group are all together, the zippy, off-color dialogue really starts to pop, especially when handled by Keegan-Michael Key and Thomas Jane. Holbrook, meanwhile, is a bland choice for our hero, while Moonlight's Trevante Rhodes exudes the kind of cool you'd want from a leading man.
But ultimately it makes sense that the biggest star on the TIFF red carpet was a person in a Predator suit, because all the actors take a backseat after the arrival of a Predator jacked like Arnold Schwarzenegger. Why he has this new physique is something I won't spoil yet, but let's just say there's some internal conflict among our not-so-friendly extraterrestrials over how to deal with the human race. This plot development boils down to a final moment that basically screams sequel. And, no, it's not an Alien vs. Predator. It's more like Advanced Humans vs. Predator. It's exhausting.