If you do life right, you'll live and die in San Francisco... in which case you've hopefully got some time to cross all of these must-do, only-in-SF items off of your bucket list. If you do life wrong, you'll end up moving back to whatever nowhere town you came from. In which case, you have less time to do all of these must-do, only-in-SF things, so get on it now.
Either way... what are you waiting for? There are sights to be seen, foods to be eaten, drinks to be drunk, and merriment to be made. And all of it can only be accomplished in the best city on earth.