True Fact: the term "remote possibility" was derived from the gravely slim chance of figuring out which remote went with which device, which is why a GW grad has just created Surc, a combo iPhone app/physical tool that'll let you clutterlessly manage “virtually all the infrared-controlled devices in your life”.
Fit your phone in the case (which looks a lot like the standard little rubber ones) and download the app, and you'll be able to start organizing your devices by room after first finding them in Surc's enormous database of TVs, stereos, and lighting systems; on the off chance you have something they don't (sick MiniDisc player dude!), just hold your physical remote parallel to Surc and it'll use infrared magic to import its functions.
The thing also lets you create a universal remote for each room so you can turn off everything with one click, and you can personalize each remote's screen by moving the buttons around, and hiding or deleting ones you don't need, so like, "on" for that MiniDisc player.
Best of all, you can pair different buttons/functions with Wii-style gestures like swiping and shaking, an anger-induced reaction that you thankfully won't have anymore, what with your newfound freedom from losing/mixing up remotes.