As outlined in the video above, the show would have been very different. However, a few holdovers from the original concept remained. For instance, "Human Flesh," the pilot episode, had the Belchers get a health inspection from Linda's old flame Hugo, who suspects that there's human flesh in the burgers.
That episode also features them grinding meat in the basement, a bit like how Sweeney Todd deposited bodies in the basement of his barbershop for Mrs. Lovett's meat pies. The episode also introduces Mort the mortician who owns a funeral home next door. That would be an easy source of "ingredients" for the cannibal burger shop. If not Mort's dead bodies, then maybe their need for people meat is the reason that the business to the right of the store in the opening credits changes every episode.