Clearly some of these would be a more practical career switch than others, and many of them require some higher education. If you're 20 years into a career as a holiday card writer, the 14 years of training you'll need to become a physician probably won't square. A career in the tech industry might be more practical, like working as a senior software engineer for $119,791 a year. You might even get by without a computer science degree, but you will need to get really good at coding. Also, if you have a high threshold for tedium and numbers, consider becoming a tax manager or actuary for $108,515 and $111,474, respectively. Those gigs require some certifications, but they'll pay more than apprenticing under a master puzzle maker.
If you're still in school or early in your career, maybe go for gold and become a neurologist and make $217,837 a year. You'll need to complete a grad degree and years of residency training, but at the end of all that you'll be well-paid and have a job that helps people, which is the exact recipe for feeling good about yourself at a cocktail party.