It's probably immediately apparent that there's a big difference between the number of jobs available at the top and bottom of this list. San Francisco, which came in first, has around seven times as many high-paying positions as San Diego did in last. But you'll also be living in the most expensive city in the country, so your $100,000 won't go as far even if you do get a job there. Also, in other cities, there will be fewer tech bros -- a privilege upon which you can't put a price.
New York is the only real competition for SF when it comes to volume of jobs. But Washington, DC, Los Angeles, and Boston all have a significant amount of top-paying gigs. And you could probably find positions outside tech in those cities, and, again, since you'll be paying less, you'll have more money to do fun things and actually enjoy your well-funded life.
If you're more interested in the salary than the location, peruse this list of the companies with the most jobs paying over $100,000 jobs right now.