While Chrome users have been able to mute individual tabs for a while, the new update that rolled out Wednesday adds the ability to mute an entire website. That means that once you mute a particular site in one tab, it automatically mutes any subsequent tabs of that website you may open. In a word, it's genius.
To take advantage of it, you simply right click the tab in question and select "Mute Site" from the dropdown. If and when you want to turn the audio on a page back on, just right click and select "Unmute."
Your muting preferences will only last as long as you keep the browser open, and things will reset when you quit and restart Chrome.
Now go forth, and browse without fear of being unexpectedly blasted by the sound of rogue autoplay ads when you just wanted to read the news.