While the Moon likely won't get in your way, there's a chance that clouds could obstruct your view if you're attempting to watch from much of the East and the Great Lakes. However, folks in the northern Plains, the Southeast, and much of California will have ideal weather for watching the show, according to a report by AccuWeather. But no matter where you are, it's probably going to be chilly, so be sure to dress warm and pack yourself a hot toddy to sip while you look up.
Perhaps the biggest challenge you'll face is getting far enough from the light pollution of the city or suburbs, so check out this handy dark sky map to track down the darkest areas near your location. Thankfully, you don't have to bother with binoculars or telescopes to fully enjoy the meteors, but you will need to give your eyes some time to adjust to the darkness before the height of the shower arrives.