As the researchers explain, in mixtures that contained 45 vol-% of ethanol, guaiacol rose to the top of the mixture, giving the drink a more robust and traditional whiskey tang. In less diluted mixtures containing 59 vol-% of ethanol, researchers found that "guaiacol is increasingly surrounded by ethanol molecules and is driven to the bulk" of the drink, where the flavor can often spread out and become muddled. Of course, this only means adding a small dash of water, not a full glass or a fistful of ice cubes, will augment your whiskey experience.
Which is to say that your sanctimonious liquor pretensions are all for nought, as proven by science. So savor the flavor of a whiskey neat, but just know that a dash of water might go a longer way than you previously thought.