Hollywood and Highland
Who: Clefairy, Meowth, Vulpix, Kakuna, Onix
The center Elephant courtyard has three lures, often lit up, which attract rare Pokemon. You can battle at the nearby TCL Chinese Theater, a Pokémon gym; this Clefairy was spotted window-shopping at Victoria’s Secret.
Who: Meowth, Pinsir, Ponyta, Raticate, Rhyhorn, Venonat
You’ll find them in Little Tokyo, which has dozens of PokéStops.
Who: Seel, Shellder, Goldeen, Horsea, Magikarp, Tentacool
The Long Beach boardwalk and Downtown attracts several rare types, including water Pokémon like Poliwag, Poliwhirl, and Dratini.
Overall pro tip: Though unproven officially, it’s thought that rare types spawn where there are a lot of players, which is why high-density PokéSpots like tourist destinations, theme parks (Disneyland, Universal Studios, Six Flags, Knott's) and malls (Grove, American in Glendale) have higher rare sightings.
Also: always incubate your eggs, which can hatch rare Pokemon.
And since Niantic, the developers of the Pokemon game for Nintendo, have an LA office, we bet there are some rare Pokemon there too.