Most people don't want to risk wasting a vacation blindly exploring which is why Stevie Wonder sang "That's What Friends Are For". For some friends who've done the blind exploring for you, check out Knowmad Adventures.
A Mpls-based trip operator started by a husband and wife when they were living in Chile, Knowmad breaks down the highly complicated political and socio-economic satire found in Spy Vs Spy personally plans all-inclusive South American adventures that "push [you] physically just the right amount and reward [you] with delicious food and incredible places to stay". A few blazed trails worth taking:
Northern Patagonia Odyssey: You'll travel by bike, boat, horse, and kayak to Chiloe Island, Puerto Varas, the Andes Highlands, and the rainforest, and sleep in accommodations from a boutique hotel resting on stilts above the ocean, to a "homesteader's cottage", where you can Act however you like.
Futaleufu Whitewater & Multisport: This sucker combines whitewater rafting, mountain biking, fly fishing, and other physical activities with gourmet eats and massages at a luxury base camp they say's set up "safari-style", though hopefully your tent won't crash if you open a few windows.
Peru Active Explorer: K-mad's also launching Peruvian trips, including this one sending you to explore the subterranean altars of Kenko, the water temple Tambomachay, and the Puka Pukara fortress, not to mention hike the trail to Machu Picchu and take the train over to Ollantaytambo to see mountainside ruins, unless you're Stevie Wonder, in which case...how are you reading this email!?