Party in Quito's La Mariscal neighborhood in Plaza Foch, the main nightlife zone filled with bars, clubs and restaurants. In Guayaquil, head to Las Penas; it may look shady from afar, but it's actually one of the safest areas in town. You'll find small dive bars throughout, several with karaoke as part of their lineup (we warned you, it's big).
For smaller beach towns, there's Montanita, a surfer hippie escape with open-air cafes and bars that stay open until dawn. As for what you'll be imbibing, the popular beer is a pale lager called Pilsener, and the must-try cocktail in the Andes is the Canelazo, a spiced cinnamon/sugar cane hot rum libation that's the perfect end to any meal.
Correction: The original version of this article stated Ecuador uses the peso as currency. The current version has been updated to correct this error.
Andrew Villagomez is a freelance writer and blogger who covers travel, men's fashion, and other lifestyle topics. Along with Thrillist, he has also contributed to Travel + Leisure, Details, Passport, and Essential Homme. Check out his blog, and follow him on Twitter and Instagram at @VeeTravels