Thanks to IFC's satirical sketch comedy and cult fave, Portlandia, the city between the Columbia and Wilamette Rivers has learned to laugh at their hipster musicians, bearded hippies, and holier-than-thou locavores. One thing they don’t joke about, though, is their beer; at the forefront of the ongoing craft beer craze, the Portland metro area boasts 71 breweries (that's NOT a typo), the most of any city in the world. In case you're wondering, Oregon as a state currently has 153 breweries in operation. Drop by Breakside, Cascade, Hair of the Dog, or Upright to start, and then knock off a few more the following afternoon. When you’re ready to pass out, head to the 57-room Kennedy School hotel, which has a brewery on site.