11. Memphis, TN
If all you know about the home of the blues is Elvis Presley, or (god forbid) that awful "Walking in Memphis" song, consider this your crash course in "What Makes Memphis Musically Relevant 101." Yes, the King is Memphis' favorite son, but this town has also produced such notable acts as Justin "Derrrty Pop" Timberlake, the former lead singer of Saliva, Josey "Oh, that dude?" Scott, and Aretha Franklin, who needs no nickname.
Beale Street's the big musical draw here for visitors with even half a clue, and while it's certainly worth checking out BB King's Blues Club, the locals forego Beale's neon, touristy splendor for smaller venues like Hi-Tone Cafe and Young Avenue Deli, or larger national acts performing at Minglewood Hall, FedExForum, or the Bartlett Performing Arts Center.