California Route 1 -- United States
The route: This prime 655mi stretch of motorway sandwiched between the mountains and ocean of California's western coastline can only be described as the quintessential road trip. Turns out SoCal and NorCal are connected by more than an affinity for kale, as Route 1 runs all the way from Los Angeles to San Francisco, or San Fran to LA, depending on you perspective. Either way, expect to pay out the roof if you're renting a convertible.
Pit stop: Check out Big Sur (the town, not just the region), specifically the Big Sur Tap House. Here you'll score a mix of friendly locals, tasty brews, and some insider travel tips, like the season's best camping spots.