Why you need to go: The most important wine region in Mexico (yes, Mexico has wine!) is crawling with roadtrippers and wine enthusiasts. Just a two-hour drive from the San Diego border, Guadalupe Valley in Baja California has luxury design hotels, top Mexican chefs opening trendy restaurants, and, naturally, excellent vineyards in which to frolic. Or, taste wine. It’s one of the most scenic, rural spots in Mexico with valleys unfurling for miles under vast blue sky.
The one must-do thing: While wine tasting is obvious, you'll absolutely want to try some of the region’s best restaurants.The al fresco Finca Altozano, helmed by popular chef Javier Plascencia, serves up seasonal, traditional Mexican dishes. Laja, touted as the best restaurant in Baja California, dishes out an excellent, farm-fresh tasting menu. And La Villa del Valle, an intimate six-room hotel, features a cool taco truck.