Located inside the W Hotel, SoBou is a spirited restaurant south of Bourbon St (hence the name) feels like a modern-day Creole saloon. The restaurant and lounge is known for its hand-crafted cocktails, and serves creative spins on traditional bar snacks like crispy pork skin and spicy beer nuts, as well as some heartier dishes. SoBou also has a beer garden with beer taps in the tables and self-serve wine machines.
With a 13-star flag hanging in front, Red Hook's Fort Defiance nods to American history in more ways than one. The menu is rooted in American cookbook classics but sprinkled with European flavors: deviled eggs are topped with fried capers and roasted chicken is served with creamy polenta and braised Tuscan kale. Regular specials like burger nights, oyster happy hours, and the weekly Sunken Harbor Club, a celebration of Tiki food and drink, keep this neighborhood spot lively. That said, you can always count on weekend brunch.
The 50-suite Hotel Monteleone's a 19th-century Royal St landmark. The suites are capped with a 24-hour fitness center, spa, and heated rooftop pool, and night-capped by the haunted lobby's historic revolving Carousel Bar.