Venue Info

Known For

Sandwiches

Seafood

No one does po-boys like Domilise's. The Uptown spot has been owned by the same family for over 100 years, which accounts for the consistently good eats and veritable Southern hospitality that has brings regulars back time and time again. While you really can't go wrong with anything on the menu, we suggest you stick to the seafood and opt for a fried oyster or catfish po-boy. If the handpainted sign overhead isn't enough of an indication that you've arrived at this cozy, yellow house on the corner, the steady line of regulars waiting for a table likely will.

Best po-boys in New Orleans at Domilise's Uptown

Domilise's Po-Boys

Flickr / sanfranannie

No one does po-boys like Domilise's. The Uptown spot has been owned by the same family for over 100 years, which accounts for the consistently good eats and veritable Southern hospitality that has brings regulars back time and time again. While you really can't go wrong with anything on the menu, we suggest you stick to the seafood and opt for a fried oyster or catfish po-boy. If the handpainted sign overhead isn't enough of an indication that you've arrived at this cozy, yellow house on the corner, the steady line of regulars waiting for a table likely will.